Our research program focuses on the development of new molecules and devices that enable biological activities to be measured and manipulated.  The projects underway involve aspects of diverse disciplines ranging from materials chemistry to chemical biology and nanotechnology.


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Advances in genomic and proteomic methods now allow classification of disease based on molecular profiling. The detection of a molecular analytes and use of this type of information for disease diagnosis requires methods with…..

Controlling the intracellular localization of synthetic molecules is essential for effective drug development. Nonetheless, rational control over intracellular trafficking of small molecules has remained a challenge. The Kelley lab has ….

Controlling the intracellular localization of synthetic molecules is essential for effective drug development. Nonetheless, rational control...

The worlds of biology and semiconductor engineering have traditionally been quite distinct. The spontaneous assembly of biological materials presents a ….